Emerging trends and hotspots in chronic obstructive pulmonary disease and oxidative stress: a bibliometric and visualized analysis from 2010 to 2024

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Key findings

• Oxidative stress is a prominent area in chronic obstructive pulmonary disease (COPD) studies. “Exposure (to air pollution)”, “cigarette smoke extract”, “mitochondrial dysfunction”, and “antioxidant” are becoming hot topics.

What is known and what is new?

• Although oxidative stress has a substantial impact on the progression of COPD, there has been a deficiency in bibliometric analyses focusing on research trends and hotspots in the field.

• This study conducted a comprehensive and visual analysis in the field of oxidative stress and COPD, providing new ideas for future scientific research.

What is the implication, and what should change now?

• The key role of oxidative stress in the occurrence and development of COPD has been confirmed, but the efficacy of antioxidants developed from oxidative stress in the treatment of COPD is limited. Follow-up research should be continuously strengthened to develop precisely targeted antioxidants that effectively act on specific cellular compartments.

Publication: Wang R, Feng S, Jiang J, Chang Y, Zong Y, Guo J. Emerging trends and hotspots in chronic obstructive pulmonary disease and oxidative stress: a bibliometric and visualized analysis from 2010 to 2024. J Thorac Dis 2025;17(3):1228-1248. doi: 10.21037/jtd-24-1679