About The Study: In this randomized clinical trial, home high-intensity aerobic training improved ataxia symptoms, fatigue, and aerobic fitness more than dose-matched home balance training among individuals with cerebellar ataxias, a heterogenous group of disorders characterized by progressive disability due to loss of coordination. Individuals in the aerobic group who continued to train regularly maintained benefits at 1 year.
Corresponding Author: To contact the corresponding author, Scott Barbuto, MD, PhD, email sb3779@cumc.columbia.edu.
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(doi:10.1001/jamaneurol.2025.3421)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented as a poster during the annual meeting of the American Neurological Association.
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Journal
JAMA Neurology