About The Study: The findings of this cohort study suggest that poverty and social disadvantage, characterized by low educational level and household income among both women and men, were associated with lower fecundability (defined as the per-month probability of conceiving) and increased risks of subfertility (defined as a time to pregnancy or the duration of actively pursuing pregnancy of more than 12 months or use of assisted reproductive technology) but not with miscarriage risk. Further studies are needed to identify the underlying and explanatory mechanisms associated with fertility outcomes and the potential for novel public health strategies for couples desiring pregnancy.
Corresponding author: To contact the corresponding author, Vincent W. V. Jaddoe, M.D., Ph.D., email v.jaddoe@erasmusmc.nl.
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(doi: 10.1001/jamanetworkopen.2025.32741)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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