About The Study: In this randomized clinical trial, among adult patients receiving mechanical ventilation in the intensive care unit (ICU), a low-use wrist-strap physical restraint strategy compared with a high-use strategy did not reduce days free of delirium or coma at 14 days.
Corresponding Author: To contact the corresponding author, Romain Sonneville, MD, PhD, email romain.sonneville@aphp.fr.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2026.2897)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented at the 45th International Symposium on Intensive Care and Emergency Medicine.
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Journal
JAMA