About The Study: In this cohort study of dementia-free older adults, anemia was associated cross-sectionally with higher levels of Alzheimer disease blood biomarkers and longitudinally with increased dementia risk. The highest dementia risk occurred when low hemoglobin and elevated Alzheimer disease biomarkers coexisted, suggesting a potential interplay between anemia and neuropathology in dementia development.
Corresponding Author: To contact the corresponding author, Martina Valletta, MD, email martina.valletta@ki.se.
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(doi:10.1001/jamanetworkopen.2026.4029)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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