Biomedicine and pharmacotherapy are multidisciplinary fields of research offering vast knowledge which has lead to significant developments in global health care. The valuable understanding in fields like molecular medicine, immunobiology, gene therapy, drug delivery and discovery, cancer biology, pharmacogenomics, pharmacology, chemical biology, physiology, and basic or clinical research has attracted great interest among researchers and motivates them to investigate and augment the remedial assistance in various diseases. Following these contemplations, the book series, BenthamBriefs in Biomedicine and Pharmacotherapy aims to cover new trends and techniques in these fields in the form of unique volumes. Overall, the book series will also help in the understanding of recent and future trends in drug discovery aspects of biomedicine. Of these, the first volume is Oxidative Stress and Natural Antioxidants. Free radicals are extremely reactive, short-lived molecules with unpaired electron valency. Antioxidants are stabilizing agents of free radicals in the body. Physiological homeostasis between the generation and elimination of free radicals must be maintained, for normal functioning and the regulation of cell signaling processes. Oxidative stress occurs if there is an imbalance in physiological homeostasis, where the production exceeds the elimination rate of free radicals. The main objective of this volume is to provide a comprehensive resource for interested readers on oxidative stress and free radical medicine. Topics included range from an understanding of oxidative stress, recent advances in preparation methods, characterization, and applications of antioxidants.
About the Editors:
Dr. Pardeep Kaur is M.Sc. (Hons.), M.Phil., and Ph.D. in Botany from Guru Nanak Dev University, Amritsar. Her research interests include medicinal plants, multi-herbal combinations, natural plant products, in-vitro/in-vivo evaluation of plant extracts or isolated compounds for different bioactivities, and determining the molecular mechanisms of action. Dr. Kaur has published articles in peer-reviewed international journals with a cumulative impact factor of more than 50. She is also a reviewer of international scientific journals.
Dr. Rajendra G. Mehta is an internationally known researcher in the area of cancer chemoprevention, drug discovery, and molecular mechanism of drug action. The main focus of research in his laboratory has been in the fields of carcinogenesis and chemoprevention for the past 40 years. Over the years, his group has discovered several products as a possible cancer preventive and therapeutic agents. These include Resveratrol (from red wine), 1 alpha hydroxy-Vitamin D5 (vitamin D analog), Deguelin (from African plants), and Fenretinide (retinoid, vitamin A analog). In addition, he developed a procedure called mouse mammary gland organ culture model (MMOC) to screen newly identified (or synthesized) chemicals from plants for their cancer-preventive properties. The National Cancer Institute (NCI, USA) is using this procedure for screening compounds.
Keywords:
Antioxidants, Inflammatory Diseases, Oxidative Stress, Carcinogenesis, Phytochemicals, Immunity, Drugs and Xenobiotics, Probiotics, Environmental Pollutants, Myocardial infarction, Redox Homeostasis, Nutraceuticals, Free Radicals, Alzheimer’s Disease, Biochemical Analysis, Glutamate Neurotoxicit, Antioxidants Extraction, Genistein
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