News from Science China Press

A propensity score-matched cohort study compared kidney-sparing surgery with radical nephroureterectomy in patients with ureteral urothelial carcinoma. After matching, radical nephroureterectomy was associated with better overall and cancer-specific survival, especially in selected subgroups. The findings support refined risk stratification and careful patient selection

A study by researchers from the Department of Reproductive Medicine, Jinling Hospital Affiliated to Nanjing University, and Medical School of Nanjing University suggests that antibiotic residue-related exposure may impair spermatogenesis by disturbing mitochondrial function. The researchers further found that DHA, an omega-3 fatty acid, may help protect spermatocytes by restoring ER–mitochondria communication and reducing oxidative stress.

Not all lung cancers with the same common genetic driver respond equally to powerful targeted drugs. Researchers have now discovered why: subtle differences in the 3D shape of the mutated protein. By classifying these shapes, they identified a subtype that poorly binds to latest-generation drugs, explaining worse outcomes. The good news? Starting with a drug-chemo combo likely overcomes this resistance, offering a clear path to personalize first-line treatment.

A collaborative team from Tsinghua University, UCAS, and University of Macau has published a comprehensive review on electroactive materials for bioelectronics and regenerative medicine. The article outlines mechanisms, interfaces, and applications of conductive, piezoelectric, triboelectric, thermoelectric, and photoelectric materials, and proposes a framework guiding next‑generation bioelectronic system design.

A new study published in National Science Review has revealed that global warming may reshape the distribution of sunlight reaching Earth’s surface. Climate models project reduced downward surface solar radiation over polar regions but increased radiation over Northern Hemisphere mid-latitudes, especially in local summer. The contrast is driven by increased atmospheric water vapor, reduced mid-latitude clouds, and enhanced polar cloud liquid water.