Patients who use semaglutide for weight loss, like Ozempic, are more likely to continue the medication if they perceive it as effective, even when facing unpleasant side effects, according to Rutgers Health researchers.

Their study, published in Journal of Medical Internet Research, found perceived effectiveness – reductions in weight, appetite or food cravings – was the strongest predictor of satisfaction and intention to continue treatment, regardless of side effects.

UC Irvine scientists used directed evolution to engineer a DNA polymerase that can quickly and accurately produce RNA, overcoming a fundamental limitation of natural enzymes.

The new enzyme, C28, synthesizes RNA with high fidelity, supports long sequences, and enables reverse transcription and DNA-RNA amplification, expanding experimental capabilities.

The National Science Foundation supported the research.