Q&A: How do infections get past the placenta’s defenses?
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Updates every hour. Last Updated: 8-Nov-2026 16:16 ET (8-Nov-2026 21:16 GMT/UTC)
Providing effective literacy learning tools and instruction for children with autism provides many challenges, but results from an ARC Linkage Project that continued through COVID-19 lockdowns highlighted the effectiveness of online teaching programs.
Every dollar spent on COVID-19 vaccine development and distribution generated an estimated $59.70 to $809 in economic value during the first year that vaccines were given, according to new research published in the journal PLOS Medicine.
The study—the first global analysis of the return on investment for COVID-19 vaccines—shows that vaccines not only averted severe illness and saved lives, but were also a sound investment.
- A Cambridge team led by Professor Jonathan Heeney has used AI to engineer vaccine antigens for a new candidate bird flu vaccine that outperforms current stockpiled jabs, which are made from single virus strains recommended by the World Health Organisation.
- The new broad-spectrum vaccine provides complete protection against diverse bird flu variants, trials in animals show.
- The result follows successful animal trials of broad-spectrum vaccines for coronavirus and swine flu, designed using the same platform.
- Earlier this year the team announced that their broad-spectrum coronavirus vaccine had proved safe in human clinical trials.
- The new study provides further evidence that the team’s ‘plug and play’ approach could be used to create safe, highly effective vaccines for a plethora of infectious diseases threatening human health globally, including Ebola and Marburg viruses, amongst some of the most dangerous human pathogens in the world.
- This new class of vaccines moves us closer to a wide variety of broadly protective vaccines in the future - including safer, much more effective seasonal Flu jabs. They not only protect against many variants simultaneously, but may also provide protection against related viruses that have not yet emerged or spilled over into humans.
- The technology could be a game changer for pandemic preparedness, health security and national biosecurity. It could help translate global surveillance data into broad protective immunity, before outbreaks become established epidemics or pandemics.
UC San Diego study identifies new potential treatment targets for COVID-19 and other diseases caused by coronaviruses.
Determining whether one variable truly causes another – rather than merely correlating with it – usually requires deliberate intervention experiments, which are often impossible in climate systems, neural circuits, or economies. Reporting in The Innovation, researchers led by Professors Wei Lin, Luonan Chen, and Kazuyuki Aihara introduce a theoretical framework called interventional dynamical causality (IntDC) together with a computational criterion, interventional embedding entropy (IEE). Built on delay-embedding state-space reconstruction, IEE quantifies the strength of intervention-level causal effects using observational time-series data alone – no manipulation of the system required. The method accurately removed confounding effects in benchmark simulations and successfully reconstructed the neural connectome of Caenorhabditis elegans, COVID-19 transmission networks in Japan, and circadian gene regulatory networks.
Today, @AmerGeriatrics released their findings from the AGS Older Adults Vaccine Initiative in @AGSJournal. Read more at: https://doi.org/10.1111/jgs.70770
Early Paxlovid treatment was associated with modestly lower risks of Long COVID, post-acute hospitalization, and death among high-risk, nonhospitalized patients with COVID-19, while no clear reduction in Long COVID risk was observed among low-risk patients.
A new national study found that hospitalizations for serious heart infections associated with drug use are declining after years of increases, driven largely by a decrease in opioid-associated cases.
Published today in Clinical Infectious Diseases, the study analyzed national hospitalization data from 2016 through 2022 to identify trends in drug use-associated infective endocarditis. Researchers identified more than 118,000 hospitalizations nationwide during the seven-year period. Hospitalizations peaked at approximately 18,700 in 2020, during the COVID-19 pandemic, before declining by 18% to about 15,300 in 2022.
Infective endocarditis is a potentially life-threatening infection that occurs when bacteria or other germs enter the bloodstream and infect the inner lining or valves of the heart. The infection, which can occur when people inject drugs, can cause permanent heart damage, require lengthy hospital stays or lead to death.
Stimulants outnumbered opioid cases in parts of the country
The researchers also pointed out another key finding: while opioid-associated hospitalizations are declining, stimulants such as methamphetamine and cocaine are accounting for a growing share of these serious infections, particularly in the Western part of the United States.
The researchers estimated a 59% probability of stimulant-involved infective endocarditis in the Pacific region, compared to 34% in New England.
Nationwide, in 2016, approximately 37% of drug use associated endocarditis hospitalizations involved stimulants, either alone or in combination with opioids. By 2022, that proportion had increased to nearly 47%.
“I believe the problem isn't simply that stimulants are becoming more prominent. It's that the healthcare system currently has fewer effective tools to treat stimulant use disorder than opioid use disorder,” said Christine.