Latest news releases from NIH-funded organizations

Funded Research News

Updates every hour. Last Updated: 6-Dec-2025 19:11 ET (7-Dec-2025 00:11 GMT/UTC)

24-Nov-2025

New study shows species-specific ‘shedding’ could distort efficacy of cancer drugs targeting TIGIT

University of California - Davis Health
Peer-Reviewed Publication

Anti-TIGIT immunotherapy drugs behave differently in macaques and humans. The findings may explain why immunotherapy anti-TIGIT antibodies have failed in Phase III trials.

Journal

Journal of Biological Chemistry

Funder

NIH/National Cancer Institute, Ovarian Cancer Alliance of Greater Cincinnati

24-Nov-2025

Many who die by suicide aren’t depressed, genetic research suggests

University of Utah Health
Peer-Reviewed Publication

Half of people who die by suicide have no diagnosed psychiatric risk factors, such as depression. It was unclear whether this population was depressed and undiagnosed, or simply not depressed. Genetic research shows that this population is less likely to have genetic risk factors for depression, suggesting that what puts them at risk is meaningfully different.

Journal

JAMA Network Open

Funder

NIH/National Institute of Mental Health, NIH/National Institute of Mental Health, NIH/National Institute of Mental Health, NIH/National Institute of Mental Health, Janssen Research and Development, American Foundation for Suicide Prevention, National Alliance for Research on Schizophrenia and Depression, National Alliance for Research on Schizophrenia and Depression, National Alliance for Research on Schizophrenia and Depression, Clark Tanner Foundation

24-Nov-2025

Scientists get detailed look at part of a cellular ‘stress’ warning protein

Johns Hopkins Medicine
Peer-Reviewed Publication

In an effort to reveal the inner workings of a protein that serves as a cell’s damage detection system, scientists at Johns Hopkins and the Ludwig-Maximilians-University Munich (LMU) have published what is believed to be the first 3D details of the ZAK protein’s structure. 

Journal

Nature

Funder

NIH/National Institutes of Health, Howard Hughes Medical Institute, U.S. National Science Foundation, European Research Council, National Key R&D program of China, Damon Runyon Cancer Research Foundation, Johns Hopkins University Provost’s Postdoctoral Fellowship Program, Dermatology Foundation’s Dermatologist Investigator Research Fellowship

24-Nov-2025

Most homemade dog diets lack nutrients, Texas A&M study finds

Texas A&M University
Peer-Reviewed Publication

Over the last two decades, homemade diets have seen a rise in popularity among dog owners. However, new research from the Dog Aging Project (DAP) reveals that most homemade diets are missing important nutrients that dogs need to lead healthy lives.

Journal

American Journal of Veterinary Research

Funder

NIH/National Institute on Aging

24-Nov-2025

New clues to why some animals live longer

University of California - Riverside
Peer-Reviewed Publication

A collaborative study by scientists at the University of California, Riverside, and University of Southern California reports on how a process known as alternative splicing, often described as “editing” the genetic recipe, may help explain why some mammals live far longer than others.

Journal

Nature Communications

Funder

NIH/National Institutes of Health