15-Apr-2025 Do “harm reduction” interventions for substance use lower or raise trust in government? Annenberg Public Policy Center of the University of Pennsylvania Peer-Reviewed Publication A paper by psychologists at the University of Pennsylvania's Annenberg Public Policy Center suggests that public perception of governmental support for comprehensive drug policies, including harm reduction, is a postive predictor of trust in local government. Journal Harm Reduction Journal Funder NIH/National Institute on Drug Abuse
15-Apr-2025 MDI bio lab patents, publishes novel method to inhibit melanin production MDI Biological Laboratory Peer-Reviewed Publication Bar Harbor, Maine — A new study led by MDI Biological Laboratory identifies ML233 as a potent inhibitor of melanin production, offering promise for development of new treatments for pigment-related skin disorders and one melanoma subtype. The compound showed strong effects at low doses in zebrafish, mouse and and human cell models, highlighting potential for dermatological therapies. Journal Communications Biology Funder NIH/National Institute of General Medical Sciences, NIH/National Institute of General Medical Sciences, NIH/National Institute of General Medical Sciences
14-Apr-2025 Children’s Hospital of Philadelphia researchers chart natural history of patients with SCN8A-related disorders Children's Hospital of Philadelphia Peer-Reviewed Publication Researchers have completed a comprehensive natural history study of SCN8A-related disorders, which represent a spectrum of neurological symptoms. The study, using retrospective clinical information analyzed through novel data analysis methods, revealed a range of seizure types and neurodevelopmental features, and identifies potential targets for future clinical trials. Journal Neurology Funder The Cute Syndrome Foundation, NIH/National Institute of Neurological Disorders and Stroke, Children's Hospital of Philadelphia
14-Apr-2025 Researchers develop an LSD analogue with potential for treating schizophrenia University of California - Davis Peer-Reviewed Publication UC Davis researchers have developed a new, neuroplasticity-promoting drug closely related to LSD that harnesses the psychedelic’s therapeutic power with reduced hallucinogenic potential. Journal Proceedings of the National Academy of Sciences Funder NIH/National Institutes of Health, Camille and Henry Dreyfus Foundation, Boone Family Foundation, Hope for Depression Research Foundation, Pritzker Neuropsychiatric Disorders Research Consortium, L.I.F.E. Foundation, Chan Zuckerberg Initiative, U.S. National Science Foundation, Delix Therapeutics
14-Apr-2025 To avoid parasites, some fruit flies sacrifice sleep University of Cincinnati Peer-Reviewed Publication Some fruit flies sacrifice sleep to avoid parasites like mites. Researchers discovered marked differences in gene expression related to metabolism in the hypervigilant flies. Funder U.S. National Science Foundation, U.S. Department of Agriculture, NIH/National Institute of Allergy and Infectious Diseases