Combination treatment harnesses cellular recycling system to fight multiple myeloma
Peer-Reviewed Publication
Updates every hour. Last Updated: 29-Oct-2026 10:16 ET (29-Oct-2026 14:16 GMT/UTC)
New research out of VCU Massey Comprehensive Cancer Center provides promising evidence for an innovative combination treatment strategy that uses cells’ waste removal functions to effectively dismantle multiple myeloma. The findings, published recently in Cell Death & Disease, show how an experimental targeted protein degrader, developed in-house at the cancer center, enhances the destruction of a specific cancer cell survival protein and works in tandem with existing drugs in preclinical models, while showing limited toxicity in cardiac models.