Researchers at the Broad Institute and The Jackson Laboratory have used prime editing, a precise and versatile form of gene editing, to correct the root cause of alternating hemiplegia of childhood (AHC), a debilitating genetic condition, in mice. The team used a scalable approach to develop prime editing treatments that directly repaired five different AHC-causing genetic mutations. Mice that received the treatment had far fewer and less severe symptoms of AHC, and survived more than twice as long as untreated mice.

A new online tool developed by researchers at the University of Louisville promises to speed up the discovery of treatments for brain and nerve tumors, especially rare ones that have had limited research attention.