A genomic analysis traces Indian ancestry back to a migration out of Africa around 50,000 years ago, after which humans interbred with Neanderthals and Denisovans and spread throughout Eurasia. About 10,000 years ago, farmers from Iran and nomadic herders from the Central Asian steppe mixed with the local hunter-gatherers. Then, 5,000 years ago, endogamy led to bottlenecks. This complex evolutionary history has shaped the genetic variation and health and disease in India.

In experiments with healthy volunteers undergoing functional MRI imaging, scientists have found increased activity in two areas of the brain that work together to react to, and possibly regulate, the brain when it’s “feeling” tired and either quits or continues exerting mental effort. 

Serious quality defects were found in a significant number of cancer medications from sub-Saharan Africa, according to new research from the University of Notre Dame.

A new study involving 121 former elite rowers from Australia has revealed one in five develops atrial fibrillation (AFib).

This common heart rhythm condition can lead to stroke and heart failure in some individuals, but the researchers identified new genetic and clinical tools that enable early preventive strategies.