New step toward programmable chemistry may help reduce drug side effects
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-Oct-2026 22:17 ET (29-Oct-2026 02:17 GMT/UTC)
Drug delivery and diagnostic imaging often lack specificity, but a new “TRACE” method lets specially‑caged compounds stay inert until a target cell’s enzymes quickly remove the cage, potentially allowing for more precise drug delivery and sharper diagnostic imaging.
Gladstone Institutes has received an initial award of $2 million from the National Institute of Allergy and Infectious Diseases (NIAID), with additional funding of up to a total of $10 million available over the proposed 5-year project period. This grant will establish the Center for PhAIge Therapy, a research center that will develop new phage-based treatments for antibiotic-resistant bacterial infections.