New preclinical research from the Fralin Biomedical Research Institute at VTC suggests that resistance training may offer greater protection against obesity and type 2 diabetes than endurance exercise. In a study published Oct. 30 in the Journal of Sport and Health Science, Zhen Yan and colleagues developed a novel mouse model that mimics weightlifting and compared it directly to voluntary running in mice fed a high-fat diet. 

Unnaturally repeating copies of genetic code called tandem duplications within the UBTF gene lead to a high-risk form of acute myeloid leukemia, UBTF-TD AML, which is known for treatment resistance and relapse. Researchers found that these copies give rise to an anomalous transport signal not found in the naturally occurring UBTF protein.