Research points to new therapies to lessen the severity of delusions for patients with schizophrenia
Peer-Reviewed Publication
Updates every hour. Last Updated: 29-Oct-2026 01:16 ET (29-Oct-2026 05:16 GMT/UTC)
New research has found that improvements to the severity of delusions in patients with schizophrenia-spectrum disorder recovering from an acute psychotic episode were significantly associated with reductions in volatility priors—someone’s expectations about the unpredictability of their environment. The findings from the new study, appearing in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, suggest that volatility priors are modifiable, pointing to a potential novel treatment target.