A collaborative team led by Ravi Radhakrishnan of the School of Engineering and Applied Science and Jake Brenner and Jacob Myerson of the Perelman School of Medicine at the University of Pennsylvania has unraveled the mathematics of a 500-million-year-old protein network that acts like the body’s bouncer, “deciding” which foreign materials get degraded by immune cells and which are allowed entry. “This discovery enables us to design therapeutics the way you’d design a car or a spaceship—using the principles of physics to guide how the immune system will respond—rather than relying on trial and error,” says Brenner.

A new cooling technology could significantly improve the energy efficiency of data centers and high-powered electronics while reducing water use associated with cooling. By passively removing heat through evaporation, it offers a promising alternative to traditional cooling systems.

A research team has developed a microbubble-based nano-gene delivery platform (BTN MB) that precisely delivers gene suppressors into bacteria to effectively remove biofilms formed by the super bacteria Methicillin-resistant Staphylococcus aureus (MRSA)

Princeton Plasma Physics Laboratory unveils a machine with unmatched capabilities to explore the phenomenon known as magnetic reconnection.

In a world first, a team led by researchers at Penn State used two-dimensional materials, which are only an atom thick and retain their properties at that scale, unlike silicon, to develop a computer capable of simple operations. The advancement, published in Nature, represents a major leap toward the realization of thinner, faster and more energy-efficient electronics, the researchers said.

For the first time, scientists have used Earth-based telescopes to look back in time over 13 billion years to get a clearer picture of one of the least understood epochs in the history of the universe, the Cosmic Dawn.