TRIM21 knockdown mitigates the effects of NKAPL on NSCLC cell phenotypes. (IMAGE)
Caption
(A) A549 and H460 cells were transfected with si-TRIM21 or co-transfected with si-TRIM21 and NKAPL-GFP overexpression plasmids. The expression level of TRIM21 was verified by western blotting. (B) Cell proliferation was determined by a CCK8 assay. (C) Changes in cell migration and invasion capacity were evaluated via transwell assays. (D) Schematic illustration of the regulation of NSCLC malignant progression by NKAPL. The data were presented as mean ± standard deviation (n = 3). **P < 0.01 and ***P < 0.001.
Credit
Genes & Diseases
Usage Restrictions
Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted.
License
CC BY-NC-ND