Assessment of the haplotype-resolved MHC assemblies of the tumor cell lines. (IMAGE)
Caption
(A) The continuity of targeted assembled MHC haplotypes of the A549 cell line by comparing with the MHC region of the GRCh38 reference. The Y-axis illustrates the coordinates from the targeted assembly, whereas the X-axis denotes the coordinates from the GRCh38 reference. (B) The completeness of assembled MHC haplotypes for each cell line evaluated with BUSCO. The bar chart illustrates the proportions of the various states of the CEGs within the assemblies. "n" represents the total count of CEGs within the MHC region. (C) The Merqury evaluation of the completeness of assembled MHC haplotypes. Quality value (QV) was determined by a log-scaled probability of error for the consensus accuracy.
Credit
Haozhe Yuan, Mengping Jiang, Xingyu Xu, Jialiang Zhu, Shulong Dong, Weida Meng, Dandan Zhang, Jiakang Ma, Yicheng Lin, Ziqiang Chen, Shaoyang Sun, Wenqing Qiu, Yun Liu
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CC BY-NC-ND