RAB26 promotes prostate cancer proliferation and metastasis in vivo. (IMAGE)

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RAB26 promotes prostate cancer proliferation and metastasis in vivo.

Caption

(A) Gross view of mice and tumors. (B) Growth curve of tumor volume. (C) The weight of the tumor. (D) Representative hematoxylin-eosin staining images in the xenograft model of prostate cancer. (E) Western blotting verified the expression of RAB26 in tumor tissue. (F) Representative immunohistochemistry images of epithelial-mesenchymal transition-related markers in tumor tissue. (G) Representative immunohistochemistry images of Bmil, NANOG, and SOX2 in tumor tissue. (H) Imaging of living small animals and gross images of lung metastases. (I) Representative hematoxylin-eosin staining images of a lung metastatic tumor. (J) Representative immunohistochemistry images of MMP2 and MMP9 in lung metastatic tumor. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, and ∗∗∗∗p < 0.0001.

Credit

Hexi Wang, Simin Liang, Xiaoyi Du, Guozhi Zhao, Yuanyuan Bai, Junwu Li, Haoyu Xu, Senlin Peng, Ye Yuan, Wei Tang

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CC BY-NC-ND

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