VDR expression is reduced in the endometrial tissue of patients with IUA compared to normal endometrial tissue. (IMAGE)
Caption
Next-generation transcriptome sequencing identified differential mRNA expression between normal endometrial tissue (N1–N3) and endometrial tissue from patients with IUA (P1–P3).
(A) Heatmap.
(B) KEGG analysis of differentially expressed genes between the normal and IUA endometrial tissues.
(C) Immunohistochemistry was used to detect VDR expression in endometrial tissues from patients with IUA and normal endometrial tissues.
(D, E) Western blot analysis was performed to measure VDR expression in endometrial tissues from patients with IUA (n = 5) and in normal endometrial tissues (n = 5).
Student’s t-test was used for continuous variables between two groups (n = 5). Error bars indicate the standard error. The symbols ∗ and ∗∗ denote p < 0.05 and p < 0.01, respectively. Scale bar: 100 μm.
Credit
Hongtao Zhu, Bo Yang, Hui Wang, Ping Nie, Xixi Wu, Ming Yong, Xingwei Jiang, Jianguo Hu
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