GXYLT2 inhibited the tumorigenicity of GC cells. (IMAGE)
Caption
(A) Tumor growth curves of MKN45 cells with GXYLT2 knockdown (sh2) or control (shC) (n = 4/group). (B, C) Tumor image
(B) and weight (C) of MKN45 xenografts (sh2 and shC).
(D) Western blotting analyses for GXYLT2 and c-Myc protein expression in MKN45 xenografts (sh2 and shC).
(E) Immunohistochemistry staining for Ki67 expression in MKN45 xenografts (sh2 and shC). Scale bar, 25 μm.
(F) The percentage of Ki67+ cancer cells was quantified in MKN45 xenografts (sh2 and shC). Data were presented as mean ± standard deviation. p-values were calculated with one-way ANOVA (A) and two-tailed unpaired student's t-test (C and F). ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001. GXYLT2, glucoside xylosyltransferase 2; GC, gastric cancer.
Credit
Jiale Yang, Jiajun Wu, Ziqiang Chen, Xiangyun Hou, Xiaojing Li, Zhaorui Liu, Kai Yin, Tao Pang, Ruimin Huang, Jun Yan
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