Translational roadmap for engineered mitochondrial delivery. (IMAGE)
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Schematic overview of the translational pathway for engineered mitochondrial delivery, covering manufacturing, quality control, storage, delivery, biodistribution, safety, efficacy, patient selection, and regulatory development. The roadmap highlights how GLP, GCP, and GMP frameworks may guide the development of engineered mitochondria from standardized organelle products to clinically testable therapies.
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©Science Bulletin
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