In vivo hemodynamics monitoring of rat brain cortex (IMAGE)
Caption
a, Planar image of the rat brain cortex at 685 nm. ROIs indicated by the dashed rectangles were selected on the middle cerebral vessel and cortex areas for visualization of the longitudinal hemodynamics. b, Extracted optical absorption map at 685 nm. A tissue-vessel area was used to quantify spatial resolution in the absorption map, as indicated by the red dashed line. c, The normalized line profile of absorption values is shown for the tissue-vessel area in (b) and used as edge spread function (ESF). The line spread function (LSF) was calculated by taking derivative of the ESF, and the spatial resolution, measured as the FWHM of the LSF, was 120 μm. d, The functional chromophore concentrations and oxygenation level were monitored at 15 Hz for over 30 s. The time series of those physiological parameters is shown for the three representative ROIs, respectively.
Credit
by Yanyu Zhao, Bowen Song, Ming Wang, Yang Zhao, and Yubo Fan
Usage Restrictions
Credit must be given to the creator.
License
CC BY