Effect of extracellular vesicles isolated from oral cancer cells on the radioresistance of oral cancer. (IMAGE)
Caption
A. Transmission electron microscopy images of extracellular vesicles isolated from radiation-sensitive (top) and radiation-resisitant (bottom) cells. The lower left square is a magnified image. B. Fluorescence microscopy images of extracellular vesicles taken up by radiation-sensitive cells. Upper: Extracellular vesicles derived from radiation-sensitive cell (green) are incorporated into a radiation-sensitive cell (blue). Lower: Extracellular vesicles derived from a radiation-resistant cell (red) are incorporated into a radiation-sensitive cell (blue). C. Change in radioresistance when extracellular vesicles are incorporated into a radiation-sensitive cell. The graphs show the cell viability under each condition. Gray: no treatment, Blue: treated with extracellular vesicles of radiation-sensitive cells, Red: treated with extracellular vesicles of radiation-resistant cells.
Credit
From Figs. 1D, 2D & 2E of Yamana K., et.al., Journal of Extracellular Vesicles, 2021. The image has been modified for use and clarity within this release.
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