Article Highlight | 22-Jun-2025

Lack of efficacy of concomitant 5-aminosalicylic acid with vedolizumab in inflammatory bowel disease: a large-scale administrative database analysis

Osaka Metropolitan University

Researchers at Osaka Metropolitan University’s Graduate School of Medicine evaluated whether adding 5-aminosalicylic acid (5-ASA) to vedolizumab therapy helps prevent relapse in ulcerative colitis (UC) and Crohns disease (CD). Using a large Japanese claims database, the team found no benefit of 5-ASA in maintaining remission for either UC or CD. These findings suggest that combining 5-ASA with vedolizumab may not be beneficial.

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