Immunity for the long haul: Why some antibodies are built to last
Peer-Reviewed Publication
Updates every hour. Last Updated: 20-Oct-2026 14:16 ET (20-Oct-2026 18:16 GMT/UTC)
A team led by the University of Osaka researchers discovered that cells producing IgG1 antibodies multiply more, are less prone to cell death in the spleen, and migrate more efficiently to the bone marrow, where long-lived antibody-producing cells can become established. Understanding how these cells gain these advantages could help researchers design vaccines that provide longer-lasting protection against infection.
Nanographenes can be considered as molecular fragments of graphene, a 2D conductive material in which carbon atoms are connected in a honeycomb pattern. Because their electronic and photophysical properties vary depending on the size and shape of the molecule, nanographenes are expected to find applications in OLEDs, organic solar cells, organic field-effect transistors, and more. For this, simple methods to synthesizing nanographenes that avoid complex multi-step processes are desired. Now, a team of scientists from WPI-ITbM at Nagoya University and from RIKEN have established a new two-step annulative p-extension (APEX) method that generates structurally diverse nanographenes. This research was published online in the scientific journal Angewandte Chemie International Edition on August 25.