News from Science China Press

Recently, the archaeometry team from University of Chinese Academy of Sciences, in collaboration with National Center for Archaeology, Key Laboratory of Archaeological Sciences and Cultural Heritage, Chinese Academy of Social Sciences, Institute of Archaeology of the Chinese Academy of Social Sciences, and Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, utilized paleoproteomic technology to reveal that the feather decoration unearthed from Tomb No. 1 at Wuwangdun (Tomb of King Kaolie of Chu) of the late Warring States period (the late 3rd century BCE) were crafted from the feathers of multiple bird species, and that the used animal glue originated from the extinct short-horned water buffalo (Bubalus mephistopheles). This research not only fills the gap in the scientific analysis of archaeological feather remains in China but also extends the known survival time of the short-horned water buffalo by at least 700 years. The related findings were published in Science Bulletin entitled "Proteomic characterization of feather decorations and extinct buffalo glue during early Iron Age China".

A research paper just published in Science China Life Sciences reports that a bacterial effector, delivered via a type IV secretion system, directly disarms a competitor’s type VI secretion system by hijacking its core structural component VgrG1, thereby blocking the competitor's antibacterial defense without killing it — a "win without battle" strategy.

Alterations in the bacterial composition in various anatomical sites of the human body have been associated with tumorigenesis and the progression of multiple cancers; however, divergent results regarding enriched bacteria have been reported across studies of the same disease, indicating cohort-dependent bacterial compositional variance. To move beyond this inconsistency, a research team led by Professor Na Liu from Sun Yat-sen University Cancer Center proposes a fundamental shift in perspective. The team argues that it is the functional repertoire of bacterial communities, rather than their taxonomic identity, that serves as the core driver of tumor progression. The team proposes the unified nomenclature of bacterial functional constituents as “tumor-associated bacterial effectors” (TABEs), categorizing them into six functional classes according to their chemical nature, conserved structural features, and analogous mechanisms of action in regulating host cells. The researchers believe that exploring the mechanisms of TABEs in cancer represents a critical step toward harnessing their biological potential in real-life clinical settings.

A recent review published in Science Bulletin outlines the evolving landscape of metabolic dysfunction‑associated steatotic liver disease (MASLD), emphasizing a suite of non-invasive genetic, metabolic and microbial markers that improve disease detection and prognosis, and summarising the clinical significance of the recent FDA‑approved drugs, resmetirom and semaglutide, along with a robust pipeline of late‑stage therapeutics. Crucially, the review addresses the substantial hurdles to clinical translation in newly developed biomarkers, including validation, standardization, and cost, and proposes a roadmap for translating these scientific advances into effective, personalized patient care.

How cells precisely control the timing of mRNA activation during differentiation is a longstanding question in molecular biology. In this study, researchers uncovered the MX-H pathway and MXL vesicles as the machinery responsible for removing inhibitory RNA-binding proteins and unleashing stored mRNAs at the right moment for sperm maturation. Importantly, the team found that this germ cell-specific system is hijacked by gastric cancer to promote tumor growth. These findings not only illuminate a fundamental regulatory mechanism in development but also identify a promising new target for selective cancer therapy.

Regular physical activity is a cost-effective strategy for cardiovascular health. However, comprehensive evidence on the specific impact of different exercise types remains limited. Now, a team of researchers from Fuwai Hospital, Chinese Academy of Medical Sciences published a review in Medicine Plus. It elucidates the effects of aerobic, muscle-strengthening, and combined exercises on cardiovascular diseases, summarizes underlying mechanisms, and highlights the critical value of personalized exercise strategies in health promotion.

As researchers seek better batteries beyond today’s lithium-ion technology, black phosphorus is drawing growing attention as a high-capacity anode material for lithium-, sodium-, and potassium-ion storage. A new Science Bulletin review examines both the promise and the practical barriers of this material, from structural instability to interfacial degradation, and highlights emerging strategies to address them. The article provides a clear roadmap for developing more durable, scalable, and higher-energy battery anodes for future energy-storage systems.