Researchers have shown how pre-existing immune cells in the blood may help individuals develop rapid and strong protection against hepatitis B infection following vaccination.
- University of Antwerp, Research Foundation Flanders, American Lebanese Syrian Associated Charities, National Institute of Allergy and Infectious Diseases
The 24-year-old physician Dr. Laura Hinze from Hannover Medical School receives the Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers 2022, as announced today by the Scientific Council of the Paul Ehrlich Foundation. Laura Hinze is being honoured for her significant contribution to the understanding of signal transduction in cancer cells. She has discovered how leukaemia cells develop resistance to the chemotherapeutic agent asparaginase, thereby presenting a novel target for the treatment of acute lymphoblastic leukaemia (ALL), the most common cancer in children. Her discovery also derives a new approach for the treatment of colorectal cancer and other solid tumours.
Scientists developed a multi-organoid system from human induced pluripotent stem cells (hiPSCs) to simulate human liver-islet axis in normal and T2DM.
- Advanced Science
Patients with alcohol-associated cirrhosis have poorer outcomes after ICU discharge, compared to patients with cirrhosis linked to other causes, according to new Mayo Clinic research.
- Mayo Clinic Proceedings
Studying the sensory organs of a 100-million-year-old cockroach offers new insights into how the species may have lived.
- The Science of Nature
- Kuribayashi Scholarship and Academic Foundation, Japan Society for the Promotion of Science, Canon Foundation
Scientists at NTU Singapore have developed a new therapeutic approach to obesity and related metabolic disorders that in laboratory experiments demonstrated a significant reduction in body fat, body weight, and improvement in the blood markers that accompany these disorders. This method begins with an injection of a specially developed hydrogel using an insulin needle, into a fat deposit directly under the skin. A near infrared light is then shone on the site of the injection for five minutes a few times daily, over a few days, activating the hydrogel’s fat-burning ability.
- ACS Nano
A UCLA-led cost analysis of the controversial new Alzheimer’s disease drug aducanumab shows that ancillary care services, such as additional MRIs and neurologist visits to monitor the potential brain swelling and bleeding associated with the medication, account for nearly 20% of total Medicare costs related to the drug, or $6,564 per patient per year.
- JAMA Health Forum
- NIH/National Institutes of Health
Decades of research on medical cannabis has focused on the compounds THC and CBD in clinical applications. But less is known about the therapeutic properties of cannabinol (CBN). Now, a new study by Salk scientists shows how CBN can protect nerve cells from oxidative damage, a major pathway to cell death. The findings suggest CBN has the potential for treating age-related neurodegenerative diseases, like Alzheimer’s.
- Free Radical Biology and Medicine
Analysis of top-ranked primary care journal before and during pandemic found pandemic disproportionately affected women. Publications are ‘hallmarks of tenure decisions’ and boost promotions and raises. Burnout, childcare and eldercare responsibilities may be impacting publication rates.
- The Annals of Family Medicine