Scientists at The Jackson Laboratory have discovered how aging blood stem cells acquire mutations that give them a growth edge, creating fertile ground for the development of clonol hematopoiesis, a condition that dramatically increases the risk of heart disease, blood cancers, and other illnesses. Importantly, they’ve also identified a method to halt this abnormal growth. This breakthrough provides crucial insight into age-related blood disorders and opens the door to new therapeutic strategies targeting the root cause of these conditions.