In one of the largest head-to-head tau PET comparisons conducted to date, PET tracer MK6240 identified 23 additional tau-positive cases per 100 scans in cognitively healthy people with amyloid pathology, compared to Flortaucipir.

Researchers at LSU's Pennington Biomedical Research Center, in collaboration with investigators from 32 countries participating in the SUNRISE International Study, have published new findings examining how restrained sitting contributes to daily movement patterns in early childhood. Led by postdoctoral researcher Dr. Katherine Spring, "Probability of meeting the restrained sitting guideline in early childhood: an international cross-sectional study," published in the Journal of Science and Medicine in Sport, explored how time spent restrained in devices such as car seats and strollers may influence children's ability to meet movement behavior recommendations during a critical stage of development.

Researchers at Columbia University Irving Medical Center have identified a gene that drives the development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease. The study, to be published May 28 in the Journal of Experimental Medicine (JEM), shows that genetic or pharmacological inhibition of Sirtuin 1 prevents the growth of NEPC tumors in mice, and lays the groundwork for future clinical studies aimed at developing new treatments for NEPC in humans.