3D-printed device advances human tissue modeling
Peer-Reviewed Publication
Updates every hour. Last Updated: 27-Oct-2025 07:11 ET (27-Oct-2025 11:11 GMT/UTC)
A collaborative team of researchers led by vision scientists from the School of Veterinary Medicine at the University of Pennsylvania have developed new tools to improve gene therapy in advanced stages of inherited retinal diseases (IRDs) such as retinitis pigmentosa and Leber congenital amaurosis. “This study addresses one of the biggest hurdles in IRD treatment: how to deliver effective gene therapy after a large portion of the retina has already degenerated,” says Raghavi Sudharsan of Penn Vet.
Proteins catalyze life by changing shape when they interact with other molecules. The result is a muscle twitching, the perception of light, or a bit of energy extracted from food.
Research from a team at University of Michigan reveals that for Ce. elegans worms, the presence of dead members of their species has profound behavioral and physiological effects, leading them to more quickly reproduce and shortening their lifespans.