Fatal drug overdoses among youth aged 15 to 24 in the United States involving synthetic opioids alone—not mixed with other substances—soared by 168 percent over the five-year time period of 2018 to 2022, a new study shows. Publishing online May 20 in the journal Pediatrics, the work also found that youth overdose rates and drug combinations varied significantly across age, sex and race/ethnicity.

Women with a higher McCance Brain Care Score (BCS) – a score that measures physical, lifestyle, and social-emotional factors – have a lower risk of experiencing a stroke or other cerebrovascular event reducing blood flow to the brain, according to a new study conducted by experts from Mass General Brigham. The results are published in Neurology, the medical journal of the American Academy of Neurology.

Postpartum depression (PPD) affects up to 15 percent of individuals after childbirth. Early identification of patients at risk of PPD could improve proactive mental health support. Mass General Brigham researchers developed a machine learning model that can evaluate patients’ PPD risk using readily accessible clinical and demographic factors. Findings demonstrating the model’s promising predictive capabilities are published in the American Journal of Psychiatry.