Figure 1. CHD8-induced chromatin remodeling. (IMAGE)
Caption
Figure 1. CHD8-induced chromatin remodeling.
In chromatin found in the nucleus, DNA is highly folded and packed into structures known as nucleosomes, where the DNA is wrapped around proteins called histones. Gene expression is regulated by the decondensation and condensation of the chromatin. CHD8 possesses chromatin remodeling activity that alters chromatin structure, thereby regulating the switching of gene transcription between on and off states.
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© Nishiyama, M. et al., Kanazawa University (2026)
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