Study reveals how a rare pediatric liver cancer emerges
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Jun-2026 16:16 ET (23-Jun-2026 20:16 GMT/UTC)
A study reveals that a rare pediatric liver cancer arises from multiple liver cancer cells that independently undergo tumor-type transitions into other tumor types.
New molecular insights into the link between hepatocellular carcinoma and intratumoral fibrosis could lead to better treatment strategies, report researchers from Institute of Science Tokyo. Through a comprehensive analysis involving clinical data and in vitro and in vivo experiments, they revealed that the SPP1–CD44–Hedgehog signaling pathway is a key driver of fibrosis in liver tumors, hinting at its potential as a therapeutic target.
Women are more likely to survive cancer than men but face a higher risk of serious and adverse side effects from treatment, according to a landmark international study from Adelaide University.
Published in the Journal of the National Cancer Institute (JNCI) and conducted in partnership with a international collaborators, the research identified consistent differences between male and female cancer patients in both survival and treatment toxicity.
Female patients had a 21% lower risk of death compared with male patients, yet a 12% higher risk of severe toxicities.
One in ten emergency patients with visible blood in their urine die within three months of presenting at A&E, new research has found. The WASHOUT study, presented at the European Association of Urology Congress (EAU26) in London, found that a scan within 48 hours could reduce this risk.