New University of Calgary research reveals that eliminating a single gene improves immunotherapy for colorectal cancer — a fundamental breakthrough.

Spatial profiling of muscle-invasive bladder cancer reveals how different tumor cell states are organized within individual tumors

Bladder tumors are not simply “luminal” (more differentiated) or “basal” (less differentiated) but often contain both cell states arranged in distinct spatial patterns

Luminal tumor cores and basal-like invasive regions respond differently to treatments

Findings provide a framework that may inform precision therapy strategies tailored to the spatial tumor cell landscape of bladder cancer