EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 23-Jun-2026 05:16 ET (23-Jun-2026 09:16 GMT/UTC)

New research shows how AI may help avoid unnecessary chemotherapy for breast cancer patients

RCSI
Peer-Reviewed Publication

Research led by RCSI University of Medicine and Health Sciences and University College Dublin (UCD) has identified immune markers that could help doctors more accurately determine which breast cancer patients are unlikely to benefit from chemotherapy, potentially sparing some patients from unnecessary treatment.

Journal: Nature Communications

New framework renders AI trustworthy for cancer subtyping

Vanderbilt University Medical Center
Peer-Reviewed Publication

Reported June 23 in Nature Biomedical Engineering, researchers at Vanderbilt Health and centers in Hong Kong have created a versatile uncertainty-aware AI framework broadly adaptable as a wrapper for digital pathology AI systems. (An AI wrapper acts as an interface layer that customizes, formats and automates how users interact with the underlying intelligence.) They demonstrate their wrapper, called TRUECAM, primarily with reference to non-small cell lung cancer (NSCLC) subtyping using whole-slide images.

Journal: Nature Biomedical Engineering

Rise in colorectal cancer among young adults in Germany as well — but below US levels

German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)
Peer-Reviewed Publication

Colorectal cancer is generally considered a disease of older adults. However, a new analysis of German cancer registries shows that the number of new colorectal cancer cases among younger adults has risen slightly over the past two decades. Those most affected are people between the ages of 20 and 39. The findings are based on data from ten German cancer registries and cover the period from 2003 to 2023.

Journal: International Journal of Cancer

Deciphering stochastic fluctuations in living cells using label-free interferometric scattering microscopy

Chinese Society for Optical Engineering
Peer-Reviewed Publication

A study published in PhotoniX Life presents a label-free method for mapping subcellular dynamics using wide-field interferometric scattering (iSCAT) microscopy and power spectral density (PSD) analysis. By fitting the pixel-wise PSD of iSCAT signals to an inverse-power-law relationship over 30–1,250 Hz, the researchers generated spectral exponent maps that visualize the characteristics and strength of subcellular motion. The method distinguished between mitotic and interphase cells, between live and apoptotic cells, and among thyroid cancer cell subtypes with increasing malignancy, highlighting a potential intrinsic optical marker for mechanobiology, cancer research, and stem cell assessment.

Funder: National Research Foundation Singapore, Startup Grant from Nanyang Technological University, Ministry of Education, Singapore AcRF Tier 2 Grant, AcRF Tier 1 Grant

Immediate treatment of moderate pre-cancerous cervical cells may be safely delayed without raising cancer risk

American College of Physicians
Peer-Reviewed Publication

A target trial emulation study found that of women with cervical intraepithelial neoplasia (CIN) grade 2 (CIN 2), a moderate form of pre-cancerous cervical dysplasia, excision within 6 months did not lower three-year cervical cancer risk compared to continued surveillance.

Journal: Annals of Internal Medicine

Pancreatic cancer discovery advances toward first-of-its-kind clinical trial

University of Miami Miller School of Medicine
Peer-Reviewed Publication

Sylvester researchers identified IL1RAP as a key driver of pancreatic cancer treatment resistance. Backed by a V Foundation grant, the findings are advancing into a first-of-its-kind clinical trial combining IL1RAP-targeted therapy with chemoimmunotherapy before surgery.

Journal: JCI Insight

Foundational research points to new therapeutic strategies for an emerging cancer drug

Salk Institute
Peer-Reviewed Publication

Salk Institute researchers investigated the impacts of entinostat, a drug that targets HDAC proteins, and found it inactivates DNA damage repair genes in pancreatic cancer cells. Their discovery led to new treatment strategies that pair entinostat with DNA-damaging therapies, as well as the development of a nanoparticle-based delivery approach that limits toxicity by selectively delivering entinostat to tumors. The findings could improve treatment outcomes and expand therapeutic options for pancreatic cancer, and similar strategies could be applied for treating other cancer types that resist DNA-damaging therapies.

Journal: Proceedings of the National Academy of Sciences

New AI-powered platform helps researchers find promising cancer therapies faster

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

The technology could help researchers identify promising cancer therapies more rapidly and provide a way to test treatments on a patient's own tumor cells, helping guide more personalized treatment decisions.

Journal: Nature Protocols
Funder: Air Force Office of Scientific Research, U.S. Department of Defense

Faster aging in younger generations linked to rise in early-onset cancer

WashU Medicine
Peer-Reviewed Publication

A new study led by researchers at WashU Medicine suggests that younger generations are aging biologically faster than their older counterparts. This faster biological aging was also linked to early-onset cancers.

Journal: Nature Medicine

A quantum mechanics approach to artificial intelligence can improve cancer outcomes

University of Utah
Peer-Reviewed Publication

Using principles of superposition and entanglement, an interdisciplinary research team led by the University of Utah and Huntsman Cancer Institute develop an AI framework to tailor patients' cancer treatment to their entire molecular background

Journal: APL Quantum
Funder: Utah Science Technology and Research

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