EurekAlert! Cancer Research

News Releases

Updates every hour. Last Updated: 8-Jul-2025 04:10 ET (8-Jul-2025 08:10 GMT/UTC)

8-Jul-2025

Gene networks decode human brain architecture from health to glioma

Dr. Michael C. Oldham's innovative gene coexpression analysis methods have transformed our understanding of brain cell diversity. His work spans from mapping cellular signatures in healthy brains to identifying therapeutic targets in gliomas, while addressing critical challenges in research reproducibility.

Journal: Brain Medicine
Funder: University of California, San Francisco, Program for Breakthrough Biomedical Research, NIH/National Cancer Institute, NIH/National Institute of Mental Health, NIH/National Institute of Mental Health, NIH/National Cancer Institute

8-Jul-2025

What’s behind the enormous increase in early-onset gastrointestinal cancers?

Oxford University Press USA
Peer-Reviewed Publication

A new paper in BJS, published by Oxford University Press, indicates that early-onset gastrointestinal cancer rates are rising dramatically across the globe.

Journal: BJS

7-Jul-2025

Hidden role of 'cell protector' opens cancer treatment possibilities

Walter and Eliza Hall Institute
Peer-Reviewed Publication

Landmark research on MCL-1, a critical protein that is an attractive target for cancer drug development, helps explain why some promising cancer treatments are causing serious side effects, and offers a roadmap for designing safer, more targeted therapies.

The WEHI-led discovery, published in Science, has uncovered a critical new role for MCL-1, revealing it not only prevents cell death but also provides cells with the energy they need to function.

The findings reshape our understanding of how cells survive and thrive, with implications for both cancer treatment and developmental biology.

Journal: Science
Funder: National Health and Medical Research Council, Cancer Council Australia

7-Jul-2025

Eliminating the need for lifelong immunosuppressive medications for transplant patients

Mayo Clinic
Peer-Reviewed Publication

While immunosuppressive medications are critical to prevent rejection of transplant organs, they also come with plenty of downsides. They can cause harsh side effects, like headaches and tremors, and increase the risk for infection and cancer. But what if there was a way to prevent organ rejection without using these medications?

Journal: American Journal of Transplantation

7-Jul-2025

NSF CAREER Award funds Rice project to shrink hospital-grade imaging into wearable devices

Rice University
Grant and Award Announcement

Rice’s Lei Li wins NSF CAREER Award to develop a new generation of wearable medical imaging technology capable of visualizing deep tissue function in real time.

Funder: U.S. National Science Foundation

7-Jul-2025

New precision medicine approach identifies a promising ovarian cancer treatment

Weill Cornell Medicine
Peer-Reviewed Publication

A pairing of two experimental drugs inhibits tumor growth and blocks drug-induced resistance in ovarian cancer, according to a preclinical study led by Weill Cornell Medicine investigators. The research reveals a promising strategy against this hard-to-treat malignancy, and more generally demonstrates a powerful new approach for the identification of effective regimens to treat genetically diverse cancers.

Journal: Cell Reports Medicine

7-Jul-2025

New bispecific antibody exploits immune receptor proximity to control autoimmunity

Chinese Academy of Sciences Headquarters
Peer-Reviewed Publication

Researchers from the Institute of Biophysics of the Chinese Academy of Sciences, the Grossman School of Medicine at New York University, and the School of Medicine at Zhejiang University have systematically demonstrated that LAG-3 inhibits T cell activity by positioning itself in close proximity to the T cell receptor (TCR) complex, rather than by simply binding to a ligand.

Journal: Cell

7-Jul-2025

Study identifies key genetic alterations and biomarker for blastic plasmacytoid dendritic cell neoplasm

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY – July 7, 2025 – A new research paper was published in Volume 16 of Oncotarget on June 17, 2025, titled “Genetic characteristics of blastic plasmacytoid dendritic cell neoplasm: A single institution experience.”

Journal: Oncotarget

7-Jul-2025

Common medication for lung cancer symptoms found to limit effectiveness of cancer treatment

University of Southern California - Health Sciences
Peer-Reviewed Publication

Keck Medicine of USC study reveals high doses of steroids may decrease effectiveness of certain immunotherapies for lung cancer when given before and/or during treatment.

7-Jul-2025

Key resistance mechanism in breast cancer could lead to more effective treatment

Temple University Health System
Peer-Reviewed Publication

Targeted cancer drugs known as CDK4/6 inhibitors have improved outcomes for patients with advanced or metastatic HR+/HER2- breast cancer, but many patients still eventually relapse and become resistant to therapy. New research co-headed by a Fox Chase Cancer Center scientist helps explain why — and offers three strategies for making treatment more effective.

Journal: Nature Cancer