Seeing thyroid cancer in a new light: when AI meets label-free imaging in the operating room
Peer-Reviewed Publication
Updates every hour. Last Updated: 7-Jan-2026 01:11 ET (7-Jan-2026 06:11 GMT/UTC)
Researchers at Duke University combined Dynamic Optical Contrast Imaging (DOCI) with AI to improve thyroid cancer detection and surgical planning. DOCI captures the natural autofluorescence of tissue without dyes, and machine-learning models use this data to classify cancer subtypes and generate precise tumor maps. This approach shows promise for providing real-time, label-free guidance during surgery, potentially reducing unnecessary procedures and improving patient outcomes.
A new AI model designs peptides (short proteins) that are targeted by enzymes called proteases, which are overactive in cancer cells. Nanoparticles coated with these peptides can act as sensors that signal if cancer-linked proteases are present in the body.
A recent study published in the medical journal Gut has revealed a novel cancer-promoting mechanism of Streptococcus anginosus (Sa). The research shows that methionine metabolites produced by this bacterium can significantly contribute to the development of gastric cancer.
This finding deepens the understanding of the gut microbiome’s role in cancer and opens new paths for microbiota-targeted prevention strategies.
In this system, Fc could convert overexpressed H2O2 to produce ·OH. Importantly, Cur could form dynamic boronate ester bonds with BA, and be encapsulated in SPSAs-1 through responsive chemical bond to form SPSAs-2. The acidic microenvironment and excessive H2O2 within tumor cells cause the dissociation of boronate ester bonds and β-CD/Fc complexes, releasing Cur. As a result, the GSH level could be reduced through the combination of the BA-induced GSH consumption and Cur-induced inhibition of TrxR activation, further enhancing CDT efficacy.
Scientists at St. Jude Children’s Research Hospital found that tumor cells use LINE-1 retrotransposons to restructure the genome to promote cancer gene expression.
Removing part or all of the breast during breast cancer treatment is a potential outcome for some people. Reconstructive surgical procedures often involve prosthetic implants or transplanted tissue from elsewhere in the body. So, researchers reporting in ACS Applied Bio Materials developed a prototype injectable paste derived from human skin cells that could help restore breast volume after tumor removal, with less scarring and shorter healing time than current options.