EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 24-Dec-2025 04:11 ET (24-Dec-2025 09:11 GMT/UTC)

Low daily alcohol intake linked to 50% heightened mouth cancer risk in India

BMJ Group
Peer-Reviewed Publication

Even a low daily intake of alcohol—-just 9 g or around one standard drink—is linked to a 50% heightened risk of mouth (buccal mucosa) cancer in India, with the greatest risk associated with locally brewed alcohol, finds a large comparative study, published online in the open access journal BMJ Global Health.

Journal: BMJ Global Health
Funder: Indian Council of Medical Research

Novel AI tool offers prognosis for patients with head and neck cancer

Mass General Brigham
Peer-Reviewed Publication

A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has developed and validated an artificial intelligence (AI)–based noninvasive tool that can predict the likelihood that a patient’s oropharyngeal cancer—a type of head and neck cancer that develops in the throat—will spread, thereby signaling which patients should receive aggressive treatment. The research is published in Journal of Clinical Oncology.

Journal: Journal of Clinical Oncology
Funder: NIH/National Institutes of Health, European Research Council, Radiological Society of North America, Canadian Institutes of Health Research Project Scheme

Research validates laboratory model for studying high-grade serous ovarian cancer

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY — December 23, 2025 — A new research paper was published in Volume 12 of Oncoscience on October 14, 2025, titled “Bridging clinical insight and laboratory model in high-grade serous ovarian carcinoma (HGSOC) using DNA sequencing-based profiling of TP53.”

Journal: Oncoscience

Night shifts aren’t just tiring, they can be deadly

Texas A&M University
Peer-Reviewed Publication

New research reveals that disrupting our internal body clock weakens immune defenses and fuels aggressive cancer — while pointing to a promising new treatment.

Journal: Oncogene

Review highlights novel targets in immunotherapy for multiple myeloma

Chinese Medical Journals Publishing House Co., Ltd.
Peer-Reviewed Publication

Multiple myeloma is an incurable plasma cell malignancy despite major therapeutic advances. A recent review by Chinese researchers highlights how immunotherapy is reshaping its treatment landscape. The article summarizes immune mechanisms driving disease progression and explores emerging targets, such as BCMA, GPRC5D, and FcRL5. It also presents promising approaches—antibody–drug conjugates, CAR-T cells, and bispecific antibodies—offering new opportunities for overcoming drug resistance and achieving durable, personalized cancer immunotherapy.

Journal: Chinese Medical Journal

China’s 2024 Gastroenterology Report: marked progress in endoscopy quality and disease management

Chinese Medical Journals Publishing House Co., Ltd.
Peer-Reviewed Publication

The 2024 report on China’s gastroenterology and digestive endoscopy, based on national databases, highlights increased early cancer detection, optimized care for priority diseases, and enhanced endoscopy quality, with mixed cost trends for inflammatory bowel disease.

Journal: Chinese Medical Journal

Magnetic nanomaterials to fight bone cancer and help healing

KeAi Communications Co., Ltd.
Peer-Reviewed Publication

The study reports on the development of core–shell magnetic nanocomposites coated with bioactive glass for combined bone cancer therapy and regeneration of the injured bone area. The magnetic materials showed high saturation magnetization, rapid apatite formation, and chemical stability. These multifunctional nanocomposites demonstrate strong potential to be used in hyperthermia-assisted cancer treatment and tissue engineering applications.

Journal: Magnetic Medicine
Funder: CNPq, UIDB/50011/2020, FCT/MCTES (PIDDAC), FAPEMIG

Dresden study uncovers new key mechanism in cancer cells

Technische Universität Dresden
Peer-Reviewed Publication

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology. Published in the renowned journal Nature Communications, the study shows for the first time that the protein MCL1 not only inhibits programmed cell death, but also plays a central role in tumor metabolism.

Journal: Nature Communications

MIT study: High-fat diets make liver cells more likely to become cancerous

Massachusetts Institute of Technology
Peer-Reviewed Publication

A new study from researchers at MIT and elsewhere reveals how a high-fat diet rewires liver cells and makes them more susceptible to becoming cancerous.

Journal: Cell
Funder: A Fannie and John Hertz Foundation Fellowship, National Science Foundation Graduate Research Fellowship, National Institutes of Health, MIT Stem Cell Initiative through Foundation MIT

Johns Hopkins scientists develop targeted therapy for t-cell lymphomas and leukemias

Johns Hopkins Medicine
Peer-Reviewed Publication

Researchers at the Johns Hopkins Kimmel Cancer Center’s Ludwig Center developed a new treatment that selectively targets TRBC2-positive T-cell cancers, expanding a precision approach they established in 2024 for TRBC1-positive tumors.

Journal: Nature Cancer
Funder: Virginia and D.K. Ludwig Fund for Cancer Research, Lustgarten Foundation for Pancreatic Cancer Research, Commonwealth Fund, Bloomberg~Kimmel Institute for Cancer Immunotherapy, National Institutes of Health (NIH) Cancer Center Support, National Institutes of Health (NIH) Cancer Center Support, National Institutes of Health (NIH) Cancer Center Support, NIH/National Cancer Institute, NIH/National Cancer Institute, NIH/National Institute of Allergy and Infectious Diseases, NIH/National Institute of General Medical Sciences, Blood Cancer United, Translation Research Program, the American Society of Hematology Scholar, the Swim Across America/Baltimore Translational Cancer Research, the Jerome Greene Foundation, the Cupid Foundation, the American Lebanese Syrian Associated Charities of St. Jude Children’s Research Hospital

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