Home-based monitoring could transform care for patients receiving T-cell redirecting therapies
Peer-Reviewed Publication
Updates every hour. Last Updated: 9-Dec-2025 02:11 ET (9-Dec-2025 07:11 GMT/UTC)
-Study shows T-cell redirecting therapy can safely be monitored at home, potentially eliminating routine hospitalization after CAR-T and BiTE treatments.
-Outpatient observation cut hospital stays dramatically, with no adverse safety events reported.
-This approach reduces time patients spend away from their families while also freeing up inpatient beds and cutting healthcare costs.
A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called T-cell acute lymphoblastic leukaemia (T-ALL).
A new decision framework developed by MIT researchers shows that, when patients with aggressive T-cell lymphoma relapse within 12 months of initial therapy, their chances for survival decline dramatically. This prognostic marker could help clinicians identify high-risk patients earlier.