Researchers have developed fluorescent molecules that permit imaging how DNA is packaged inside living cells at unprecedented resolution, and in preserved cells, close to the width of the double helix itself. The advance raises the possibility that one day they could train an AI to look at how DNA occupies three-dimensional space inside cells for diagnosing and treating cancer and other types of conditions.

Scientists from Gladstone Institutes, UC San Francisco, and Stanford University, in collaboration with Biohub, have unveiled a massive, high-resolution functional map of human immune cells that promises to transform our understanding of how genetics control health and disease. Published in the journal Cell, the study represents a landmark achievement in immunology and genomics. By systematically stress-testing genes across the genome in 22 million human immune cells, scientists moved beyond mere DNA sequencing to decode the dynamic circuits that govern how these genes actually work in the context of health and disease.

MYC is a common oncogene that regulates tumour growth and spread, yet no approved drugs exist to target it. Researchers have now discovered how to turn MYC's metabolic grip on cancer cells into a fatal weakness.

SMU Associate Professor Gao Yini spearheads an award-winning project to assess the short- and long-term effects of preventive healthcare policies in Singapore.

Using an emulated target trial—a rigorous study design that approximates a randomized clinical trial using real-world data—researchers compared outcomes among patients who received rasburicase within 12 hours of developing TLS with those who received it later or not at all. Patients who received early rasburicase were about one-third less likely to require dialysis or die during their hospital stay compared with those who received delayed or no rasburicase treatment.

Researchers at Columbia University have discovered a new type of cell that protects lung cancers from attacks by the immune system.

Albany, NY – State University of New York Chancellor John B. King Jr. today visited the Great New York State Fair on Student Youth Day. For the first time, current SUNY students with a valid student ID card or incoming SUNY students with an admission letter are receiving free admission on Student Youth Day. SUNY campuses are also showcasing agriculture, battery technologies, healthcare, and more.

Pre-cancerous blood cells can actively reshape their surroundings, prematurely aging cells in the bone marrow to create conditions that favor their own growth and, potentially, increase the risk of blood cancer, according to a new study by researchers at The Jackson Laboratory (JAX).