EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 12-Jul-2025 22:11 ET (13-Jul-2025 02:11 GMT/UTC)

Important step towards improving diagnosis and treatment of brain metastases

Medical University of Vienna
Peer-Reviewed Publication

Brain metastases often occur as a result of advanced cancer and, despite medical innovations, are still associated with a poor prognosis. Now, an international expert committee led by the Medical University of Vienna and the Ludwig Maximilian University Hospital (LMU) in Munich has taken an important step towards improving diagnostics and therapy monitoring. A special imaging procedure, amino acid PET, can not only improve patient care, but also advance research into the development of new treatment approaches. The first standardised criteria for the use of this method have now been published in the top journal Nature Medicine.

Journal: Nature Medicine

Biologists identify targets for new pancreatic cancer treatments

Massachusetts Institute of Technology
Peer-Reviewed Publication

Cryptic peptides, which are expressed in pancreatic cancer cells, could be promising targets for T-cell therapies that attack pancreatic tumors, according to a study from MIT and the Dana-Farber Cancer Institute.

Journal: Science
Funder: Hale Family Center for Pancreatic Cancer Research, Lustgarten Foundation, Stand Up To Cancer, Pancreatic Cancer Action Network, Burroughs Wellcome Fund, Conquer Cancer Young Investigator Award, National Institutes of Health, National Cancer Institute

MD Anderson Research Highlights for May 8, 2025

University of Texas M. D. Anderson Cancer Center
Peer-Reviewed Publication

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

Incidence rates of some cancer types have risen in people under age 50

NIH/National Cancer Institute
Peer-Reviewed Publication

Researchers at the National Institutes of Health (NIH) have completed a comprehensive analysis of cancer statistics for different age groups in the United States and found that from 2010 through 2019, the incidence of 14 cancer types increased among people under age 50.

Journal: Cancer Discovery

New stem cell model of faulty alpha cells that regulate blood sugar in diabetes

International Society for Stem Cell Research
Peer-Reviewed Publication

Recently, Quinn Peterson and colleagues from Mayo Clinic, USA, discovered a method for making human alpha cells from cultures of immature stem cells. This work was recently published in Stem Cell Reports. These stem cell-derived alpha cells very closely resembled pancreas-derived alpha cells and secreted comparable levels of glucagon. Importantly, like alpha cells in diabetic patients, the stem cell-derived alpha cells responded to culture conditions mimicking a diabetic environment with elevated glucagon secretion and dysregulation of alpha cell gene expression and physiology. Encouragingly, abnormal glucagon secretion of these cells was reversed by a drug called Sunitinib (a clinically approved anti-cancer drug). The human alpha cells described in this research will be a useful model to understand diabetic alpha cell dysfunction and to screen for new therapeutics.

Journal: Stem Cell Reports

Advanced imaging and targeted therapy help men with prostate cancer safely defer surgery and radiation therapy

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

UCLA investigators show that using advanced MRI imaging and targeted focal therapy can help many men with low- to intermediate-risk prostate cancer safely stay on active surveillance long-term, helping avoid follow-up biopsies and delay — or even avoid — invasive treatments like surgery or radiation.

Journal: The Journal of Urology
Funder: NIH/National Cancer Institute, Jean Perkins Foundation

Incidence of several early-onset cancers increased between 2010 and 2019

American Association for Cancer Research
Peer-Reviewed Publication

In the United States, breast, colorectal, endometrial, pancreatic, and kidney cancers are becoming increasingly common among people under age 50, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research (AACR).

Journal: Cancer Discovery

CDI lab demonstrates key molecular factor in exhaustion of immune cells - with treatment implications

Hackensack Meridian Health
Peer-Reviewed Publication

The critical pathway could have implications for immune system response to viral and other threats - particularly cancer.

Journal: Proceedings of the National Academy of Sciences

Discovery of a molecular mechanism that initiates colon cancer

Centro Nacional de Investigaciones Oncológicas (CNIO)
Peer-Reviewed Publication

A study by the Spanish National Cancer Research Centre (CNIO) has discovered that the shortage of the p53 protein in animal models triggers the formation of colorectal tumours

The findings pave the way to develop colon cancer prevention strategies

The study has been published in Nature Communications

Journal: Nature Communications
Funder: Spanish Ministry of Science, Innovation and Universities, Agencia Estatal de Investigación, iDIFFER network of Excellence and ERDF, Fundación BBVA, AECC, Instituto de Salud Carlos III

Moffitt researchers show that reactivity to tumor antigens is important for TIL therapy

H. Lee Moffitt Cancer Center & Research Institute
Peer-Reviewed Publication

A team of researchers from Moffitt Cancer Center has found new insight into why some lung cancer patients do not benefit from tumor-infiltrating lymphocyte, or TIL therapy. Their findings, published in Nature Cancer, may help improve future ways to deliver this cellular immunotherapy for metastatic non-small cell lung cancer.

Journal: Nature Cancer
Funder: Stand Up To Cancer, NIH/National Cancer Institute

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