4-Jun-2025
Low pH aggravates toxicity of polystyrene microplastics in crab Eriocheir sinensis
KeAi Communications Co., Ltd.Peer-Reviewed Publication
Microplastics (MPs) and freshwater acidification jointly threaten aquatic ecosystems. This 21-day study on Eriocheir sinensis revealed synergistic toxicity: combined low pH (6.5) and MPs exacerbated oxidative stress and immune suppression, disrupted the TCA cycle and arginine biosynthesis, and altered gut microbiota function. While MPs alone affected pyrimidine metabolism, acidification amplified MPs' toxicity via immune-metabolic crosstalk. The findings underscore the need to evaluate multiple stressors under climate change, providing critical insights for aquatic risk assessment.
- Journal
- Environmental Chemistry and Ecotoxicology
- Funder
- “14th Five-Year Plan” National Key Research and Development Program “Marine Agriculture and Freshwater Fisheries Science and Technology Innovation” Key Special Project, National Natural Science Foundation of China, Natural Science Foundation of Shanghai, the 2024 STCSM “Science and Technology Innovation Action Plan”, Innovation Program of Shanghai Municipal Education Commission, CARS-48