Why do haploid fish embryos usually die before they can fully develop? A new zebrafish study offers clues
Peer-Reviewed Publication
Updates every hour. Last Updated: 27-Mar-2026 02:16 ET (27-Mar-2026 06:16 GMT/UTC)
Researchers induced haploid zebrafish using UV-treated sperm and tracked why the embryos developed severe defects. They found that haploid embryos had low gastrulation and hatching rates, widespread malformations, and major changes in gene activity. The study points to disrupted FGF/Wnt signaling, mitochondrial function, ion transport, and cell-cycle control as key drivers of the lethal "haploid syndrome."
Psittacosaurus was a genus of herbivorous dinosaurs that lived in the Early Cretaceous. Since the first report of Psittacosaurus discoveries in Mongolia a century ago, at least 12 valid species have been recognized to date. The unearthed fossils cover a complete developmental sequence from newly hatched juveniles to adult individuals. Recently, a joint research team from the Dinosaur Evolution Research Center of Jilin University and the University of Toronto Mississauga analyzed 13 juvenile Psittacosaurus fossils from the same nest, all containing gastroliths. The findings have significantly reshaped the traditional understanding of their feeding behavior—even individuals under one year of age ingested gastroliths to aid in digesting tough, fibrous plants. Lithological analysis of these gastroliths indicates that the juveniles likely obtained the stones locally, with their activity confined to the western Liaoning region and showing no evidence of long-distance migration. This study highlights a relatively stable feeding strategy throughout the life cycle of Psittacosaurus, providing key insights into reconstructing the paleoecological evolution of early ceratopsians. The research has been published in SCIENCE CHINA Earth Sciences.
Although recurrent wheezing is a major respiratory disorder among infants and toddlers, standardized protocols have not been established for its diagnosis and management, owing to its diverse etiology. To address this gap, a panel of experts, convened by the Committee of Pediatrics, China Medical Education Association, has proposed novel evidence-based standardized guidelines for the clinical management of recurrent wheezing, which can serve as a benchmark for improving diagnostic accuracy and therapeutic efficacy worldwide.
The Shanghai International Communication of Chinese Culture Initiative is a joint international event hosted by ECNU Review of Education (ROE) and the Global Education Deans Forum (GEDF). The 2025 edition of this initiative was particularly notable for the Faculty of Education at East China Normal University, whose research on the new college entrance examination reform, inclusive education, and innovation-driven talent cultivation was selected to be presented at the event.