Finding the enzymatic needle in the database haystack
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Jun-2025 23:10 ET (27-Jun-2025 03:10 GMT/UTC)
A new fossil discovery technique reveals that squids originated and rapidly became abundant, diverse, and dominant in the oceans 100 million years ago, reshaping our understanding of ancient marine ecosystems.
Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Small, a weekly peer-reviewed scientific journal covering nanotechnology, published by Wiley-WCH, Germany, how short peptides self-assemble linearly on atomically-thick solid surfaces, such as graphite and MoS2. The research addresses a longstanding challenge in materials science: understanding the complex, sequence-specific interactions between peptides and solid substrates, and the critical role of local hydration structures in guiding nanoarchitecture formation. This work offers new strategies for integrating biomolecules with advanced materials in future bioelectronics and sensor devices.
Nanoparticles (NPs), materials with sizes ranging from 10 to 1,000 nm, are increasingly utilized as drug-delivery systems and in medical diagnosis. However, the impact of NPs on the structure and function of biological macromolecules like proteins remains poorly understood. Now, a recent study by researchers from Tokyo University of Science, Japan, reveals the changes in the protein structure of bovine serum albumin during interaction with different sizes of silica NPs.
Exciplex upconversion-type organic light-emitting devices (ExUC-OLEDs) can emit light at less than half the voltage needed for conventional OLEDs, but their development remained limited by strict requirements for compatible donor and acceptor materials. Now, researchers from Japan have introduced a nanometer-thin spacer layer, boosting blue light output by 77-fold compared to previously incompatible materials. With a greater choice of materials, this design opens doors to energy-efficient OLEDs for a wide range of uses.
When and where the earliest modern human populations migrated and settled in East Asia are relatively well known. However, how these populations moved between islands on treacherous stretches of sea is still shrouded in mystery. In two new papers, researchers from Japan and Taiwan led by Professor Yousuke Kaifu from the University of Tokyo simulated methods ancient peoples would have needed to accomplish these journeys, and they used period-accurate tools to create the canoes to make the journey themselves.