A potent combination of antimalarial compounds added to bed nets blocked parasite transmission in mosquitoes while circumventing insecticide resistance, according to a new study led by researchers at Harvard T.H. Chan School of Public Health. The finding dramatically expands understanding of druggable targets in mosquito-stage parasite development and lays the groundwork for a new, more effective way to prevent malaria transmission.

Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy. These delivery systems are a significant step toward future precise gene therapy to the brain that could safely control errant brain activity with high precision. In contrast, current therapies for brain disorders mostly treat only symptoms.

Mice genetically engineered to lack the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in a week.