Intellicule, a software company founded and led by Purdue University researchers, will use an SBIR Phase I grant from the NIH to develop software technology that could impact precision medicine. The Phase I SBIR project aims to expand and advance structural modeling and analysis for drug discovery using cryo-EM by utilizing state-of-the-art deep-learning techniques.

With a four-year, $3.2 million grant from the National Institutes of Health, a team from Pen State College of Medicine will develop a small, durable ventricular assist device (VAD) designed specifically for young, growing children between the ages of one and 11 years old. Currently, there are no heart pumps approved for long-term use for this age group. The device, called the PSU Child VAD, could provide long-term support for children with heart failure while waiting for a heart transplant, greatly improving quality of life and outcomes.

New non-invasive device conforms to the skull and delivers complex sequences of light through bone. Scientists tested the device on mice with neurons that were genetically modified to respond to light. With information transmitted via light, mice learned to discriminate patterns to complete tasks.