C. Ola Landgren, M.D., Ph.D., received HealthTree Foundation’s prestigious 2025 Innovation Award for his work in developing CORAL, a new research tool that leverages AI to predict individual outcomes and guide treatment decisions in patients with multiple myeloma.

At the core of each of our cells, the DNA molecule is constantly changing its configuration. When it twists or unfolds, it determines which genes are activated at each moment.

"We have shown that the way DNA twists is a layer of gene expression regulation that had previously gone unnoticed," says CNIO researcher Felipe Cortés.

Many breast cancers are treated by blocking oestrogens. Understanding on a molecular scale how this hormone works could help design better therapies, the authors suggest.

Shown in a study by researchers from CNIO and CABIMER published in 'Science Advances'.

researchers discovered that by using a ruthenium-catalysedsemi-hydrogenation process, PET waste could be depolymerised into a valuable chemical, ethyl-4-hydroxymethyl benzoate (EHMB). 

Remarkably, EHMB serves as a key intermediate for synthesising several important compounds, including the blockbuster anticancer drug Imatinib, Tranexamic acid, the base for medication that helps the blood to clot, and the insecticide Fenpyroximate.