When childhood cancer treatment ends, the emotional impact often does not. A new study published in the Nature journal Pediatric Research finds that symptoms of post-traumatic stress, anxiety, and depression remain common among childhood cancer survivors and their parents more than a year after treatment has been completed, highlighting the long-term psychological consequences of pediatric cancer.

A research team at the University of Würzburg has, for the first time, uncovered how E. coli bacteria sneak into the prostate. The discovery reveals a hidden infection pathway and opens the door to potential new treatments for bacterial prostatitis.

A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators. The findings suggest further development of this approach is merited.

In about 5–10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients. Research from Radboud university medical center and university hospital Bonn (UKB) in collaboration with researchers from Munich and Barcelona, shows that DNA analysis of colorectal polyps provides important additional information on the development of these polyps and colorectal cancer. This DNA analysis leads to better diagnostics and treatment and offers patients and their family members greater clarity. The results have now been published in Gastroenterology. 

Rates of multiple myeloma, the second most common blood cancer in the United States, are increasing and are twice as high in men than in women. A new study published by Wiley online in CANCER provides insights that may help to explain this disparity.

Immunotherapy before and after surgery improves outcomes for patients with lung cancer

Researchers find that higher bacteria levels inside tumors promote treatment resistance in head and neck cancer

Promising targeted therapies for AML and colorectal cancer

New targets identified to prevent chronic neuropathic pain after nerve injury

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable. The findings, published in Nature Cancer, provide unprecedented insight on immune dysfunction in myeloma and could lead to improved tools for predicting which patients are at higher risk of relapse after treatment.