Many experts in this field maintain that national prostate-cancer screening guidelines don’t accurately reflect the benefits of PSA screening. Based on that assumption, University Hospitals’ Jonathan Shoag, MD, and a team of researchers from Case Western Reserve University and the Case Comprehensive Cancer Center, Weill Cornell Medical Center, the Fred Hutchinson Cancer Research Center, and others, set out to assess the tradeoffs of PSA screening using long-term epidemiologic data. “No matter the assumptions,” Shoag said, “the data showed lower numbers than prior estimates, many in the low single digits, for the number needed to treat to prevent a prostate-cancer death. This result was observed in all men, and especially for Black men.” Shoag and his co-authors presented their findings in a late-breaking abstract at the American Urological Association’s annual meeting this month. Their study was published May 15 in The New England Journal of Medicine Evidence, accompanied by a Patient Platform.
- NEJM Evidence