Many experts in this field maintain that national prostate-cancer screening guidelines don’t accurately reflect the benefits of PSA screening. Based on that assumption, University Hospitals’ Jonathan Shoag, MD, and a team of researchers from Case Western Reserve University and the Case Comprehensive Cancer Center, Weill Cornell Medical Center, the Fred Hutchinson Cancer Research Center, and others, set out to assess the tradeoffs of PSA screening using long-term epidemiologic data. “No matter the assumptions,” Shoag said, “the data showed lower numbers than prior estimates, many in the low single digits, for the number needed to treat to prevent a prostate-cancer death. This result was observed in all men, and especially for Black men.” Shoag and his co-authors presented their findings in a late-breaking abstract at the American Urological Association’s annual meeting this month. Their study was published May 15 in The New England Journal of Medicine Evidence, accompanied by a Patient Platform.

New research led by investigators from Weill Cornell Medicine, Fred Hutchinson Cancer Center, University Hospitals Cleveland and Case Western Reserve University found that prostate cancer screening with the prostate specific antigen (PSA) blood test has remarkably favorable tradeoffs. This is particularly true for Black men, the investigators found, who disproportionately bear the burden of prostate cancer mortality and morbidity, and who are underrepresented in clinical trials.

Robot-assisted surgery used to perform bladder cancer removal and reconstruction, enables patients to recover far more quickly and spend significantly (20 per cent) less time in hospital

Immunotherapy after surgery helped reduce cancer recurrence in patients with urothelial cancer of the bladder or other sites in the urinary tract that had invaded the muscle and therefore posed a high risk for recurrence, according to clinical trial results presented at the American Urological Association (AUA) annual meeting in May.

Hospices often prescribe benzodiazepine and antipsychotic medicines like Xanax, Haldol and Seroquel to patients to ease end-of-life symptoms, but a new study shows very wide variation in the chances patients will get these drugs.

Life-like organ replicas - so-called 3D organoids - are a good way to research disease processes. A team from the University of Würzburg has now presented a kind of blueprint for such a model of the cervix.