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News Releases

Updates every hour. Last Updated: 16-Jan-2026 17:11 ET (16-Jan-2026 22:11 GMT/UTC)

Sylvester Cancer Tip Sheet for January 2026

University of Miami Miller School of Medicine
Reports and Proceedings

Digesting the new dietary guidelines, a "wipe test" for PFAS on firefighter gear, a potential new path for small-cell lung cancer care, RNA splicing errors in leukemia and more are in this tip sheet from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

Breakthrough non-invasive liver tumor treatment now available at Ochsner MD Anderson

Ochsner Health System
Business Announcement

Histotripsy is a non-invasive treatment, approved by the Food and Drug Administration (FDA) in 2023, that uses ultrasound energy to destroy liver tumors in a single outpatient procedure. This includes primary liver tumors originating in the liver, or metastasized tumors resulting from another cancer spreading to the liver. Histotripsy is a new option for patients with liver tumors who may not be a candidate for surgery or other traditional therapies.

The “broker” family helps tidy up the cell

Goethe University Frankfurt
Peer-Reviewed Publication

Cells must continually adjust their protein composition, which includes protein synthesis as well as degradation. Most regulated protein degradation is executed by the ubiquitin–proteasome system (UPS), in which proteins are tagged with ubiquitin and routed to a protein-shredder called proteasome. The enzyme E3 ligase plays a key role here by acting as a “broker” that mediates the labeling of the proteins to be degraded. A research team at Goethe University Frankfurt has now made the first systematic catalog and relationship map of all human E3 ligases and identified 40 of them as potential key players in emerging drug classes such as PROTACs, which are used, for example, to treat cancer.

Journal: Nature Communications

Air pollution and cardiac remodeling and function in patients with breast cancer

JAMA Network
Peer-Reviewed Publication

About The Study: In this cohort study, fine particulate matter (PM2.5) and ozone exposure was independently associated with worse cardiac remodeling and function in patients with breast cancer treated with cardiotoxic therapy. These findings highlight the importance of modifying environmental exposures to mitigate cardiovascular disease risk.

Journal: JAMA Network Open

Breast cancer risk markers linked to physical activity in adolescent girls

Columbia University's Mailman School of Public Health
Peer-Reviewed Publication

Recreational physical activity may be associated with breast tissue composition and biomarkers of stress in adolescent girls, according to a new study from Columbia University Mailman School of Public Health and the Herbert Irving Comprehensive Cancer Center (HICCC). The findings shed new light on how physical activity during adolescence—a critical period of breast development—may influence biological pathways related to future breast cancer risk.

Journal: Breast Cancer Research
Funder: NIH/National Institute of Environmental Health Sciences

Finding new cell markers to track the most aggressive breast cancer in blood

Baylor College of Medicine
Peer-Reviewed Publication

Of all the types of breast cancer, triple negative breast cancer (TNBC) is the most aggressive and lacks specific therapies. TNBC also is more likely to metastasize, or travel through the blood stream to spread to other organs, which causes most of breast cancer-related deaths each year. Until now, tracking circulating tumor cells (CTC), a powerful indicator of cancer metastasis, has been challenging because there are very few markers that specifically identify these cells. In this study, researchers at Baylor College of Medicine report a procedure that led to the identification of four new proteins on the surface of live CTCs that specifically identify these cells both in mouse models and people with TNBC.

Journal: Cancer Research Communications

Study reveals how high blood pressure increases susceptibility to heart damage caused by a key cancer treatment

Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)
Peer-Reviewed Publication

A CNIC research team has identified for the first time the biological mechanism underlying this susceptibility: high blood pressure creates a hidden metabolic vulnerability in the heart that becomes destabilized when anthracyclines are administered.

Journal: European Heart Journal
Funder: European Commission, Ministerio de Ciencia, “la Caixa” Foundation, Comunidad de Madrid

Dormant cancer cells change shape to survive immune system attack

Memorial Sloan Kettering Cancer Center
Peer-Reviewed Publication

New Memorial Sloan Kettering Cancer Center research reveals how dormant metastatic cancer cells protect themselves from the immune system by changing their shape.

Journal: Nature Cancer
Funder: NIH/National Institutes of Health

Scientists identify pre-cancerous states in seemingly normal aging tissues

Weill Cornell Medicine
Peer-Reviewed Publication

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center.

Journal: Cancer Discovery

Potential tumor-suppressing gene identified in pancreatic cancer

Tokyo University of Science
Peer-Reviewed Publication

Pancreatic cancer is difficult to treat and has a poor prognosis, but a new study from Tokyo University of Science highlights a gene that could change this outlook. By analyzing large cancer datasets, researchers found that the gene CTDNEP1 is significantly reduced in pancreatic tumors and associated with early disease progression and poorer survival. The findings suggest that CTDNEP1 may act as a tumor suppressor, offering promising opportunities for early detection and future treatment strategies.

Journal: Cancer Genomics & Proteomics

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