Study points to potential new therapies for hard-to-treat lung cancers
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Jun-2026 09:16 ET (22-Jun-2026 13:16 GMT/UTC)
Different forms of cancer cells and tumors have their own tricks for avoiding detection by the body’s immune system altogether or otherwise sabotaging any attempts to muster an immune response. In the case of the most common and difficult-to-treat form of ovarian cancer, this ability to suppress the immune system also makes the cancer resistant to treatments known as immunotherapies that seek to supercharge immune cells.
Scientists at Sanford Burnham Prebys and the University of California San Diego published findings February 25, 2026, in Cell Reports demonstrating a treatment approach in mice that allowed more tumor-fighting cells to approach tumors, shifted the behavior of other immune cells to work against tumors, and made immunotherapy more effective. The research team also uncovered what cellular changes prompted the immune system to better pierce the tumors’ veil of immunosuppression.Scientists studying the cellular origins of pineoblastoma discovered a dependency applicable to anatomically distinct brain tumor types, which may be therapeutically targetable.
A new discovery from UC San Diego researchers could enable easier treatment of high-grade serous ovarian cancer, the most common and aggressive form of ovarian cancer.