EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 3-May-2025 10:09 ET (3-May-2025 14:09 GMT/UTC)

Innovative technology enables the simultaneous delivery of two drugs to attack the tumor

Tel-Aviv University
Peer-Reviewed Publication

Researchers at Tel Aviv University have developed a new platform using polymeric nanoparticles to deliver drug pairs to specific cancer types, including skin cancer and breast cancer. The researchers explain that having both drugs arrive at the tumor site together significantly amplifies their therapeutic effects and safety profiles.

Journal: Science Advances

Blocking the cell cycle inhibitor p21 prevents regrowth in lung cancer cells

Medical Research Council (MRC) Laboratory of Medical Sciences
Peer-Reviewed Publication

Blocking the activity of a protein called p21 stops lung cancer cells entering a ‘sleep-like’ state that allows them to survive chemotherapy. Blocking p21 causes more cancer cells to die and reduces the chance of cancer coming back according to new research from the MRC Laboratory of Medical Sciences (LMS) and Imperial College London. While this research is in its early stages, it represents a crucial first step towards developing new drugs to inhibit p21 which could improve lung cancer survival.

Journal: British Journal of Cancer
Funder: Cancer Research UK, Medical Research Council

Microscopic discovery in cancer cells could have a big impact

Texas A&M University
Peer-Reviewed Publication

Led by Texas A&M University graduate students Samere Zade of the biomedical engineering department and Ting-Ching Wang of the chemical engineering department, an article released by the Lele Lab has uncovered new details about the mechanism behind cancer progression. Published in Nature Communications, the article explores the influence the mechanical stiffening of the tumor cell’s environment may have on the structure and function of the nucleus.

Journal: Nature Communications
Funder: NIH/National Institutes of Health, Cancer Prevention and Research Institute of Texas, U.S. National Science Foundation

UC Davis researchers help decode the cause of aggressive breast cancer in women of color

University of California - Davis Health
Peer-Reviewed Publication

Cancer center researchers may have uncovered the specific biomarker that causes Black women to get triple-negative breast cancer at higher rates than other women.

Journal: EMBO Reports
Funder: NIH/National Cancer Institute, NIH/National Cancer Institute, METAvivor

Prostate cancer: Major added benefit for PSMA diagnostics with gozetotide

Institute for Quality and Efficiency in Health Care
Reports and Proceedings

Gozetotide is a drug for diagnostic application in adults with prostate cancer. It is currently the only diagnostic agent that recognizes PSMA-positive prostate cancer and can therefore identify patients for whom PSMA-targeted therapy with (¹⁷⁷Lu)lutetium vipivotide tetraxetan (“Lutetium-177” for short) is an option.

Disparities and gaps in breast cancer screening for women ages 40 to 49

JAMA Network
Peer-Reviewed Publication

About The Study: The findings of this cross-sectional study underscore significant disparities and gaps in biennial mammography screening for women ages 40 to 49. Two-fifths of women in this age group did not receive biennial screening. Lower biennial screening rates were observed among racial and ethnic minority populations, sexual minority populations, rural residents, and socioeconomically disadvantaged populations. To optimize early breast cancer detection, ensuring equitable adherence to U.S. Preventive Services Task Force recommendations is crucial.

Journal: JAMA Network Open

The secret life of ALAS1: How a basic science discovery could pave the way for better sirna therapies

Memorial Sloan Kettering Cancer Center
Peer-Reviewed Publication

New findings by researchers at MSK and their collaborators at the Icahn School of Medicine point to an opportunity to improve therapies that use small RNAs to silence disease-causing genes, potentially including those involved in cancer.

Journal: Science
Funder: National Institutes of Health

Older age linked to increased complications after breast reconstruction

Wolters Kluwer Health
Peer-Reviewed Publication

For women undergoing breast reconstruction after mastectomy, older age is associated with small but significant increases in certain complications, reports a study in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Journal: Plastic & Reconstructive Surgery

Breakthrough study set to change how osteosarcomas are diagnosed and treated

University of East Anglia
Peer-Reviewed Publication

Researchers have been able to identify at least three distinct subtypes of a rare type of bone cancer for the first time, which could transform clinical trials and patient care.

Journal: Briefings in Bioinformatics
Funder: CHILDREN with CANCER UK

Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy

Compuscript Ltd
Peer-Reviewed Publication

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101441, discusses how Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy.

Journal: Genes & Diseases