The first-ever annual report from the American College of Surgeons National Cancer Database includes in-depth data on adult cancer diagnoses and treatment trends.

Knowing the precise mechanisms by which MYC drives muscle growth could prove instrumental in creating therapies that reduce muscle loss from aging, potentially improving independence, mobility and health.

BUFFALO, NY – December 3, 2024 – A new review was published in Oncotarget’s Volume 15 on November 22, 2024, entitled “Mesenchymal stem cells – the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists.”

Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder associated with liver disease, ranging from fibrosis to hepatocellular carcinoma. The disease remains asymptomatic until its final stages when liver transplantation is the only available therapy. Biomarkers offer an advantage for disease evaluation. The presence of microRNAs (miRNAs) in plasma extracellular vesicles (EVs) presents a noninvasive approach to assess the molecular signatures of the disease. In this study, we aimed to identify miRNA biomarkers to distinguish molecular signatures of the liver disease associated with AATD in AATD individuals.

New research builds on scientific understanding of how air pollution and cancer risk are distributed throughout the U.S. Air pollution, often resulting from industrial or vehicle emissions, can travel for hundreds of miles and impact the health of communities through higher rates of asthma, respiratory infections, stroke, and lung cancer. Although previous studies have identified disparities in how public health risks vary by income and race, a new study takes a detailed look across U.S. census tracts to find patterns in who is most at risk from cancer resulting from lifetime exposure to air pollution and how this risk is changing through time. 

This study highlights the effectiveness of proof-of-concept 1DZnO nanoplatforms for rapid cancer biomarker detection by examining the nanoscale integration of 1DZnO with these bioreceptors to deliver reliable photoluminescent output signals.